The application of peptides is as varied as they are themselves. The CPP (cell-penetrating peptides) have been utilized for a long time for delivering various particles and molecules in the cells. There have been massive improvements in biomedical research, and with that, more and more uses of synthetic peptides are coming to the forefront. Going by the present rate of research, the future looks bright for the use of peptides in areas as varied as cosmetics and life-saving drugs.
On that note, let’s take a closer look today at different types of synthetic peptides and their role in our lives. You can check websites like this to know more about peptides.
Gonadorelin Super Agonists
These peptides are used in the treatment of prostate and breast cancers. Though the current pharmaceutical products administered for treating cancer patients have not yet been replaced by Gonadorelin Super Agonists, the clinical trials have shown positive signs in this regard.
The market for Somatostatin Analogues is also showing signs of steady growth. These synthetic peptides are used in the treatment of carcinoid tumors, pituitary adenomas, glucagonomas, and so on. In fact, it is even useful in the treatment of acromegaly, which is a condition of over secretion of growth hormones in a person.
Two of the main drugs in this category are Lisinopril and Enalapril, and several new classes of drugs have also been introduced in this category. This class is larger than even the Gonadorelin Super Agonists, and even bigger compared to the group of Somatostatin Analogues.
HIV Protease Inhibitors
The sequence of these synthetic peptides was found through DNA sequences. Steve Kent and Dan Veber are the ones credited to have discovered the exact enzymatic activity of the HIV Protease Inhibitors. This peptide is frequently found in desmopressin, and it is widely used for the treatment of enuresis (inability to control urine).
These types of peptides are used for the treatment of osteoporosis. It is derived from three important products, namely, human, eel, and salmon calcitonin. Each of these three ingredients is equally potent in addressing the issues of bone strength and muscular agility. Calcitonin is a large peptide that has thirty-two amino acids.
These peptides have been around since the eighties. Thymopentin was one of the most well-known peptides in this class, and it was used to prevent HIV infections. It was discontinued because of the reimbursement policies offered by insurance companies. Other thymic hormones, like alpha-1 and thymosin, are still in use in the Middle East, Southern Asia, and South America.
Other synthetic peptides, like oxytocins, ACTH (124), and angiotensins, have been here for a longer time and they are being still used and produced. There is no doubt about the fact that the market for synthetic peptides. The modulation of the enzymatic activities and triggering of receptors can be made possible in targeted and specific ways by utilizing the potent tools to defeat and guard against the diseases.